J Curve in Hypertension

Hypertension and the "J-curve".

o c a ( S p levated blood pressure (BP) is one of the most common reventable causes of premature death worldwide. Approxiately 8 million deaths/year (i.e., 14% of all deaths worldwide) re directly attributable to an elevated BP, and with the orldwide prevalence of hypertension predicted to increase by ore than 50% by 2025, the magnitude of BP-related death is et to increase further (1). Abundan...

The J-Curve Phenomenon in Hypertension.

Almost immediately after antihypertensive therapy was proven effective in preventing cardiovascular events, the J-curve issue emerged as a hot topic. The Hypertension Optimal Treatment (HOT) trial attempted to address this question (diastolic blood pressure <80, <85, and <90 mm Hg) but ended up with a post hoc analysis indicating a nadir of 138.5 mm Hg systolic and 82.6 mm Hg diastolic blood pr...

The J-curve in arterial hypertension: fact or fallacy?

It is known that a large proportion of patients with arterial hypertension are undertreated. This may result in an increase of the incidence of cardiovascular events. On the other hand, aggressive reduction of blood pressure may increase cardiovascular events (J-curve phenomenon) in certain populations. This phenomenon may be seen in patients with coronary artery disease and left ventricular hy...

Retraction: The Significance of the J-Curve in Hypertension and Coronary Artery Diseases

On July 31, 2011, Korean Circulation Journal (KCJ) published a review article by Park et al. regarding the J-curve in hypertension and coronary artery diseases. However, a possibility of plagiarism has been raised in this article. The Editorial Board of KCJ has examined the review article and has requested the Committee for Publication Ethics of Korean Association of Medical Journal Editors (KA...

J Curve and Cuff Artefact, and Diagnostic Inertia in Resistant Hypertension.